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Methods of bioassay
Name of assay Target diseases of assay
Inhibition of A375 cell proliferation Cancer
Inhibition of A549 cell proliferation Cancer
Protection of Aβ(25-35)-induced neuronal death Brain, Nervous system , Others
Inhibition of AP-1 activity Immune system, Allergy , Cancer
Inhibition of calpain activity Brain, Nervous system , Cardiovascular system , Respiratory system , Digestive system , Endcrine & Metabolic systems , Immune system, Allergy , Cancer , Infective disease
Antagonistic activity for CCR3 Immune system, Allergy
Antagonistic activity for CCR4 Immune system, Allergy
Toxicity in cortical neurons Brain, Nervous system , Others
Inhibition of DU-145 cell proliferation Cancer
Protection of glutamate-induced neuronal death Brain, Nervous system , Others
Inhibition of HeLa cell proliferation Cancer
Inhibition of HIF-1α expression Brain, Nervous system , Cardiovascular system , Cancer
Induction of HSP70 Digestive system , Immune system, Allergy
Inhibition of HT-29 cell proliferation Cancer
Inhibition of IL-2 production Immune system, Allergy
Inhibition of IL-6 production Immune system, Allergy
Expression of MAP2 Brain, Nervous system
Inhibition of NF-kB activity Immune system, Allergy , Cancer
Inhibition of PANC-1cell proliferation Cancer
Inhibition of SK-N-DZ cell proliferation Cancer
Inhibition of SN12 cell proliferation Cancer
Inhibition of THP-1 cell proliferation Cancer
Inhibition of TNF-α production Immune system, Allergy
Inhibition of TR-LE tube formation Cardiovascular system , Cancer
Inhibition of ZR-75 cell proliferation Cancer
beta-hexosaminidase release Immune system, Allergy
Inhibition of OH radicals Immune system, Allergy
Inhibition of WEHI-231 cell proliferation Immune system, Allergy
Increase in cytosolic-free Ca2+ concentration Others
Increase in cytosolic-free Ca2+ concentration Others
Increase in cytosolic-free Ca2+ concentration Others
Increase in cytosolic-free Ca2+ concentration Others
Increase in cytosolic-free Ca2+ concentration Others
Inhibition of DPP4 Endcrine & Metabolic systems
Inhibition of calpain activity Brain, Nervous system
Inhibition of NFkB reporter assay Cancer
MHC class I antigen presentation Immune system, Allergy
MHC class II antigen presentation Immune system, Allergy
Inhibition of Smad1 activitiy Others
Stimulatory effect on hepatocyte growth Digestive system
Inhibitory effect on the enzyme activity of bacterial type II topoisomerase Infective disease
Inhibitory effect on the enzyme activity of amylase Digestive system
Inhibitory effect on PAI-1 production Cardiovascular system
Inhibitory effect on the enzyme activity of streptococcal NADase Infective disease
Agonist activity against AhR Endcrine & Metabolic systems
Inhibitory effect on the enzyme activity of serine-carboxyl protease Brain, Nervous system
Inhibitory effect on the enzyme activity of prolyl tripeptidyl peptidase from Porphyromonas gingivalis Infective disease
Effect on the split luciferase activity that reflects the cellular snRNP level Others
Inhibitory effect on cholesterol synthesis Endcrine & Metabolic systems
Inhibitory effect on NFAT promoter activity Immune system, Allergy
Inhibitory effect on NO production Brain, Nervous system
Cytotoxicity against PANC-1 cell Cancer
Stimulatory effect on BDNF gene expression Brain, Nervous system
Cytotoxicity against Jurkat cell Cancer
Inhibitory effect on MTH1 enzyme activity Cancer
Inhibitory effect on lipid droplet accumulation Endcrine & Metabolic systems
Inhibitory effect on NS2B-NS3 enzyme activity Infective disease
Inhibitory effect on hydrogen sulfide-producing enzyme activity Infective disease
Inhibitory effect on Toxoplasma gondii proliferation Infective disease
Inhibitory effect on the replication of Borna disease virus Infective disease
Inhibitory effect on the promoter activity of Piwil1 (Miwi) gene Others
Inhibitory effect on the promoter acitivity of retrotransposon Others
Inhibitory effect on the reverse transcriptase activity of hepatitis B virus DNA polymerase Infective disease
Inhibitory effect on the enzyme activity of SuperScript II reverse transcriptase Others
Stimulatory effect on neurite outgrowth Brain, Nervous system
Stimulatory and Inhibitory Effects on hydrolysis activity of hyaluronidase Others
Antitrypanosomal activity Infective disease
Inhibitory effect on Btg2 gene expression Brain, Nervous system
Stimulatory effect on secondary metabolite production by Aspergillus fumigatus Others
Inhibitory effect on the enzyme activity of endoplasmic reticulum glucosidase Infective disease
Inhibitory effect on the enzyme activity of galactosidase Infective disease
Inhibitory effect on the enzyme activity of allosidase Infective disease
Inhibitory effect on morphological changes of breast cancer cells Cancer
Stimulatory effect on the transcriptional regulator activity of YAP1 Cancer
Inhibitory effect on the enzyme activity of HDAC Others
Cytotoxicity against HL60 cells Cancer
Inhibitory effect on Golgi stress responses Cancer
Activation of NLRP3 inflammasome Immune system, Allergy
Extension of axons after Aβ(25-35)-induced atrophy
Inhibition of Jurkat cell proliferation
Extension of dendrites after Aβ(25-35)-induced atrophy
Inhibition of porcine pancreatic lipase
Protection of AMPA-R-induced cell death
 

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Division of Pharmacognosy,
Department of Medicinal Resources,
Institute of Natural Medicine,
University of Toyama
2630 Sugitani, Toyama 930-0194 Japan
TEL: +81-76-434-7601
FAX: +81-76-434-5064