Secoisolariciresinol Diglucoside
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| 化合物名 | Secoisolariciresinol Diglucoside |
| 動物種 | ヒト腸内細菌 フローラヒト腸内細菌 Peptostreptococcus sp. SDG-1ヒト腸内細菌 Eubacterium sp. SDG-2 |
| 代謝パラメータ | |
| 代謝物 |
Secoisolariciresinol Diglucoside
Secoisolariciresinol 4-((2S,3S)-4-hydroxy-3-(4-hydroxy-3-methoxybenzyl)-2-(hydroxymethyl)butyl)benzene-1,2-diol 04 4,4'-((2S,3S)-2,3-bis(hydroxymethyl)butane-1,4-diyl)dibenzene-1,2-diol 4-((2S,3S)-4-hydroxy-3-(3-hydroxybenzyl)-2-(hydroxymethyl)butyl)benzene-1,2-diol (2S,3S)-2,3-bis(3-hydroxybenzyl)butane-1,4-diol (+)-Enterolactone |
| 関連生薬 | |
| 参考文献 | 1) Wang L., Meselhy M. R., Li Y., Qin G., and Hattori M., Human intestinal bacteria capable of transforming secoisolariciresinol diglucoside to mammalian lignans, enterodiol and enterolactone. Chem. Pharm. Bull., 48, 1606-1610 (2000). 2) Gao J. J. and Hattori M.: Metabolic activation of lignans to estrogenic and anti-eatrogenic substances by human intestinal bacteria. J. Trad. Med., 22, 213-221 (2005). |
| 論文備考 | Incubation of secoisolariciresinol diglucoside (1) with a human fecal suspension Secoisolariciresinol diglucoside (1, 300 mg) dissolved in PYF broth (250 ml) was incubated with a human fecal suspension (50 ml) at 37°C in an anaerobic incubator for 15 h. [Wang et al., Chem. Pharm. Bull., 48, 1606-1610 (2000)] |
