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化合物名 | Bergenin |
動物種 | ヒト腸内細菌フローラ |
代謝パラメータ | |
代謝物 |
Bergenin
4-O-Methylgallic acid |
関連生薬 | 赤芽柏 |
参考文献 | 1) Hattori M., Shu Y. Z., Tomimori T., Kobashi K. and Namba T.: A bacterial cleavage of the C-glucosyl bond of mangiferin and bergenin. Phytochemistry, 28, 1289-1290 (1989). |
論文備考 | Fresh feces obtained from a healthy man was thoroughly suspended in 30 volumes or the anaerobic dilution medium by bubbling with oxygen-free CO2 and filtered through gauze to eliminate the residue. Bergenin (100 mg) was anaerobically incubated with an intestinal bacterial mixture (200 ml). The EtOAc extract was chromatographed on a silica gel column (24 x 24 cm) with CHCl3-MeOH (100:1) to yield a metabolite 4-O-methylgallic acid (73 mg). |