伝統医薬データベース　

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全16,671件中、3,401件～3,420件を表示しています。
[1] ・・・ [166] [167] [168] [169] [170] [171] [172] [173] [174] [175] [176] ・・・ [834]

6801. [生薬成分の代謝] 代謝パラメータ『Intravenous administration』

Intravenous administration 2 mg/kg (n=6) 59.4 ± 57.7 5.0 min 106.7 ± 17.1 ng/mL 3.17 ± 1.18 μg・min/mL Isovanilloylcatalpol 代謝パラメータ

6802. [生薬成分の代謝] 代謝物『Isorhynchophylline』

(E)-methyl 2-((1'S,6'R,8a'S)-6'-ethyl-2-oxo-3',5',6',7',8',8a'-hexahydro-2'H-spiro[indoline-3,1'-indolizine]-7'-yl)-3-methoxyacrylate Isorhynchophylline 3037048 C22H28N2O4 384.475 384.2049 385.2127 38

6803. [生薬成分の代謝] 代謝物『6-hydroxy-5-vinyl-3,4,6,7-tetrahydro-1H-pyrano[3,4-c]pyridin-1-one』

6-hydroxy-5-vinyl-3,4,6,7-tetrahydro-1H-pyrano[3,4-c]pyridin-1-one 6-hydroxy-5-vinyl-3,4,6,7-tetrahydro-1H-pyrano[3,4-c]pyridin-1-one C10H11NO3 193.202 193.0739 194.0817 192.0661 Swertiamarin 代謝物

6804. [生薬成分の代謝] 代謝パラメータ『Intragastric administration』

Intragastric administration 50 mg/kg 2.08 ± 0.73 h 1.12 ± 0.31 h 162.4 ± 42.8 ng/ml 524.6 ± 132.5 ng h2/ml 532.7 ± 132.2 ng h2/ml 0-t 0-∞ Ke 0.36 ± 0.10 1/h Pharmacokinetic parameters of

6805. [生薬成分の代謝] 代謝パラメータ『Intravenous administration』

Intravenous administration 10 mg/kg 1.67 ± 0.30 h Vd 2.91 ± 5.90 L/kg 5.22 ± 1.73 L/h/kg 2.13 ± 0.80 mg/L h 2.16 ± 0.79 mg/L h 0–tn 0–∞ R1, notoginsenoside R1; Rg1, ginsenoside Rg1; Rd,

6806. [生薬成分の代謝] 代謝パラメータ『Oral administration』

Oral administration 27 g/kg 4.83 ± 1.78 h 0.70 ± 0.07 h 672 ± 247 ng/ml 1810 ± 873 ng h/ml 0–∞ Ke 0.16 ± 0.06 1/h Osthol (Osthole) 代謝パラメータ

6807. [生薬成分の代謝] 代謝物『Erythrocentaurin』

1-oxoisochroman-5-carbaldehyde Erythrocentaurin 50276-98-7 C10H8O3 176.172 176.0473 177.0552 175.0395 Swertiamarin 代謝物

6808. [生薬成分の代謝] 代謝物『(R)-gentianol』

(S)-5-(1-hydroxyethyl)-3,4-dihydro-1H-pyrano[3,4-c]pyridin-1-one (R)-gentianol C10H11NO3 193.202 193.0739 194.0817 192.0661 Swertiamarin 代謝物

6809. [生薬成分の代謝] 代謝パラメータ『Oral administration』

Oral administration 125 mg/kg mixed solution (containing 25 mg costunolide and 100 mg dehydrocostuslacton) 4.967 h 9.000 h Cl/F 75.54 L/h/kg 0.024 L/h/kg 0.322 mg/Lh 0.331 mg/Lh 0–48 0–∞ V

6810. [生薬成分の代謝] 代謝物『10-Hydroxyrhynchophylline-10-O-glucuronide』

(2S,3S,4S,5R,6S)-6-((1'R,6'R,8a'S)-7'-((E)-1,3-dimethoxy-3-oxoprop-1-en-2-yl)-6'-ethyl-2-oxo-3',5',6',7',8',8a'-hexahydro-2'H-spiro[indoline-3,1'-indolizine]-5-yloxy)-3,4,5-trihydroxytetrahydro-2H-pyr

6811. [生薬成分の代謝] 代謝パラメータ『Oral administration』

Oral administration 125 mg/kg mixed solution (containing 25 mg costunolide and 100 mg dehydrocostuslacton) 5.442 h 6.000 h Cl/F 91.62 L/h/kg 0.063 L/h/kg 1.081 mg/Lh 1.091 1.091 0–48 0–∞ V

6812. [生薬成分の代謝] 代謝物『11-Hydroxyrhynchophylline-11-O-glucuronide』

6813. [生薬成分の代謝] 代謝物『10-Hydroxyrhynchophylline』

(E)-methyl 2-((1'R,6'R,8a'S)-6'-ethyl-5-hydroxy-2-oxo-3',5',6',7',8',8a'-hexahydro-2'H-spiro[indoline-3,1'-indolizine]-7'-yl)-3-methoxyacrylate 10-Hydroxyrhynchophylline C22H28N2O5 400.475 400.1998 4

6814. [生薬成分の代謝] 代謝物『11-Hydroxyrhynchophylline』

(E)-methyl 2-((1'R,6'R,8a'S)-6'-ethyl-6-hydroxy-2-oxo-3',5',6',7',8',8a'-hexahydro-2'H-spiro[indoline-3,1'-indolizine]-7'-yl)-3-methoxyacrylate 11-Hydroxyrhynchophylline C22H28N2O5 400.475 400.1998 4

6815. [生薬成分の代謝] 代謝物『』

(4aR,5R,6R)-4a,6-dihydroxy-5-vinyl-4,4a,5,6-tetrahydropyrano[3,4-c]pyran-1(3H)-one C10H12O5 212.202 212.0685 213.0763 211.0607 Swertiamarin 代謝物

6816. [生薬成分の代謝] 代謝物『2-oxo-4-(1-oxobut-3-en-2-yl)-5,6-dihydro-2H-pyran-3-carbaldehyde』

2-oxo-4-(1-oxobut-3-en-2-yl)-5,6-dihydro-2H-pyran-3-carbaldehyde 2-oxo-4-(1-oxobut-3-en-2-yl)-5,6-dihydro-2H-pyran-3-carbaldehyde C10H10O4 194.187 194.0579 195.0657 193.0501 Swertiamarin 代謝物

6817. [生薬成分の代謝] 代謝物『2-oxo-4-(1-oxobut-3-en-2-yl)-5,6-dihydro-2H-pyran-3-carbaldehyde』

2-oxo-4-(1-oxobut-3-en-2-yl)-5,6-dihydro-2H-pyran-3-carbaldehyde 2-oxo-4-(1-oxobut-3-en-2-yl)-5,6-dihydro-2H-pyran-3-carbaldehyde C10H10O4 194.187 194.0579 195.0657 193.0501 Swertiamarin 代謝物

6818. [生薬成分の代謝] 代謝物『2-(5-(iminomethyl)-6-oxo-3,6-dihydro-2H-pyran-4-yl)but-3-enal』

2-(5-(iminomethyl)-6-oxo-3,6-dihydro-2H-pyran-4-yl)but-3-enal 2-(5-(iminomethyl)-6-oxo-3,6-dihydro-2H-pyran-4-yl)but-3-enal C10H11NO3 193.202 193.0739 194.0817 192.0661 Swertiamarin 代謝物

6819. [生薬成分の代謝] 代謝物『(4aR,5R,6R)-4a,6-dihydroxy-5-vinyl-4,4a,5,6-tetrahydropyrano[3,4-c]pyran-1(3H)-one』

(4aR,5R,6R)-4a,6-dihydroxy-5-vinyl-4,4a,5,6-tetrahydropyrano[3,4-c]pyran-1(3H)-one (4aR,5R,6R)-4a,6-dihydroxy-5-vinyl-4,4a,5,6-tetrahydropyrano[3,4-c]pyran-1(3H)-one C10H12O5 212.202 212.0685 213.076

6820. [生薬成分の代謝] 代謝パラメータ『Oral administration』

Oral administration 50 mg/kg 1.212 ± 0.388 h 1.333 ± 0.408 h CL/F 0.824 ± 0.317 L/h/kg 23,318 ± 10,468 ng/mL 69,520 ± 22,927 ng h/mL 0-∞ 3.273 ± 0.365 h (0−∞) V1/F 1.428 ± 0.681 L/kg t1/2K

[1] ・・・ [166] [167] [168] [169] [170] [171] [172] [173] [174] [175] [176] ・・・ [834]
全16,671件中、3,401件～3,420件を表示しています。

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