Intragastric administration
Dose | 50 mg/kg |
K | |
T1/2 | 2.08 ± 0.73 h |
Tmax | 1.12 ± 0.31 h |
V | |
CL | |
Cmax | 162.4 ± 42.8 ng/ml |
AUC | 524.6 ± 132.5 ng h2/ml 532.7 ± 132.2 ng h2/ml |
Range of AUC | 0-t 0-∞ |
MRT | |
MAT | |
Others | Ke 0.36 ± 0.10 1/h |
Comment | Pharmacokinetic parameters of icariin, icariside I and icariside II after intragastric administration of icariin to six rats at a dose of 50 mg/kg (mean ±SD). [Xu et al., Journal of Pharmaceutical and Biomedical Analysis 45: 667–672 (2007)] |
Remarks |
Others:Others unclassified into each parameter
Comment:Comment on metabolism parameters
Comment:Comment on metabolism parameters