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化合物名 | Pseudoephedrine |
動物種 | ヒト |
代謝パラメータ | |
代謝物 |
Pseudoephedrine
|
関連生薬 | 麻黄 |
参考文献 | 1) Yan-Ming Liu, Wei Tian, Yu-Xiu Jia and Hai-Yan Yue, Simultaneous determination of methylephedrine and pseudoephedrine in human urine by CE with electrochemiluminescence detection and its application to pharmacokeinetics. Simultaneous determination of methylephedrine and pseudoephedrine. Biomed. Chromatogr., 23: 1138–1144 (2009). 2) Ma Ming, Feng Fang, Sheng Yulan, Cui Shuangjin, Liu Han, Development and evaluation of an efficient HPLC/MS/MS method for thesimultaneous determination of pseudoephedrine and cetirizine in human plasma: Application to phase-I pharmacokinetic study. Journal of Chromatography B, 846, 105–111 (2007). |
論文備考 | A novel method for the determination of ephedra alkaloids (methylephedrine and pseudoephedrine) was developed by electrophoresis capillary (CE) separation and electrochemiluminesence detection (ECL). The two ephedra alkaloids with very similar structures were well separated and detected under the optimum conditions. The proposed method was successfully applied to the determination of methylephedrine and pseudoephedrine in human urine and the monitoring of pharmacokinetics for PSE. [Liu et al., Biomed. Chromatogr., 23: 1138–1144 (2009)] |