Taxifolin
|
|
| Compound | Taxifolin |
| Animal species | human intestinal bacteria Eubacterium sp. strain SDG-2 |
| Metabolism parameters | |
| Metabolites |
(+)-(2R, 3R)-Taxifolin
(R)-3-(3,4-dihydroxyphenyl)-2-hydroxy-1-(2,4,6-trihydroxyphenyl)propan-1-one |
| Crude drug | Oriental Arborvitae Leafy Twig |
| References | 1) Wang L., Meselhy M. R., Li Y., Nakamura N., Min B., Qin G. and Hattori M.: The heterocyclic ring fission and dehydroxylation of catechins and related compounds by Eubacterium sp. strain SDG-2, a human intestinal bacterium. Chem. Pharm. Bull., 49, 1640-1643 (2001). |
| Remarks | ・Incubation of (+)-taxifolin with Eubacterium sp. strain SDG-2 (+)-Taxifolin (25 mg in 1 ml MeOH) was anaerobically incubated with a bacterial suspension (50 ml) for 3 d. The reaction mixture was then treated as usual to give compound 2 (12 mg). [Wang et al., Chem. Pharm. Bull., 49, 1640-1643 (2001)] |
