Intravenous administration
| Dose | 20 mg/kg |
| K | kel 0.193 ± 0.014 (h ± 1) serum ke 0.015 ± 0.001 (h ± 1)urine |
| T1/2 | 3.678 ± 0.250 (h) serum 47.385 ± 3.646 (h) urine |
| Tmax | |
| V | Vss 4.879 ± 0.507 l/kg |
| CL | CLrenal 0.070 ± 0.019 l/h/kg CLhepatic 0.845 ± 0.043 l/h/kg CLtot 0.915 ± 0.055 l/h/kg |
| Cmax | |
| AUC | 11.125 ± 0.658 mg ± h/ml 3.465 ± 0.056a % |
| Range of AUC | inf 72-inf extrapolated |
| MRT | 6.187 ± 0.290 h |
| MAT | |
| Others | fe 7.342 ± 1.754 % Extraction ratio (ER) 0.486 ± 0.025 |
| Comment | |
| Remarks |
Others:Others unclassified into each parameter
Comment:Comment on metabolism parameters
Comment:Comment on metabolism parameters
