Intravenous administration
| Dose | 2 mg/kg (n=6) |
| K | |
| T1/2 | 13.6 ± 4.6 |
| Tmax | |
| V | Vss 532 ± 105 mL/kg |
| CL | 75.3 ± 9.1 mL/min/kg CLR 4.1 ± 1.9 mL/min/kg CLNR 71.1 ± 8.3 mL/min/kg |
| Cmax | |
| AUC | 26.9 ± 3.3 μg・min/mL |
| Range of AUC | 0-∞ |
| MRT | 6.2 ± 0.9 min |
| MAT | |
| Others | Ae0-24h 5.5 ± 2.3 % of dose GI24h 0.71 ± 0.34 % of dose |
| Comment | |
| Remarks |
Others:Others unclassified into each parameter
Comment:Comment on metabolism parameters
Comment:Comment on metabolism parameters
