Intravenous administration
| Dose | 5 mg/kg (n=6) |
| K | |
| T1/2 | 12.2 ± 2.5 |
| Tmax | |
| V | Vss 768 ± 179 mL/kg |
| CL | 86.2 ± 16.3 mL/min/kg CLR 3.7 ± 2.4 mL/min/kg CLNR 82.5 ± 15.2 mL/min/kg |
| Cmax | |
| AUC | 59.6 ± 10.1 μg・min/mL |
| Range of AUC | 0-∞ |
| MRT | 8.0 ± 1.1 min |
| MAT | |
| Others | Ae0-24h 3.3 ± 0.6 % of dose GI24h 0.32 ± 0.26 % of dose |
| Comment | |
| Remarks |
Others:Others unclassified into each parameter
Comment:Comment on metabolism parameters
Comment:Comment on metabolism parameters
