Oral administration
| Dose | 27 g/kg |
| K | |
| T1/2 | 0.28 ± 0.09 h |
| Tmax | 0.16 ± 0.04 h |
| V | |
| CL | |
| Cmax | 102 ± 64 ng/ml |
| AUC | 23.2 ± 5.8 ng h/ml |
| Range of AUC | 0-∞ |
| MRT | |
| MAT | |
| Others | Ke 2.64 ± 0.86 1/h |
| Comment | Pharmacokinetic parameters of icariin, icariside II and osthole in rats after oral administration of Gushudan (Herba Epimedii, Fructus Cnidii, Rhizoma Drynariae and Radix Salviae Miltiorrhizae) extract (n=6). Mean±SD. [Liu et al., Journal of Chromatograph |
| Remarks |
Others:Others unclassified into each parameter
Comment:Comment on metabolism parameters
Comment:Comment on metabolism parameters
