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Mulberry Bark
Mulberry Bark
桑白皮
Market name:桑白皮
Photo location:Museum of Materia Medica, Inst. of Nat. Med.
TMPW No.:2426
Morus alba
Plant name:Morus alba
Photo location:Nara Pref, Japan
Photo date:1997
Photographer:K. Komatsu

Synonym White Mulberry Root-bark
Latin name Mori Cortex
Botanical source: Family name Moraceae
Botanical source: Plant name Morus alba Linné (IPNI:30051955-2)
Part used Root bark
Empirical criteria for quality selection The outer surface of good one is thin and yellowish-red in color. Also, there are whitely bleached ones. (TN)
Constituents Fatty acids:
Palmitic acid, Stearic acid

Triterpenoids:
α-Amyrin, α-Amyrin acetate, β-Amylin, Betulinic acid

Sterols:
Sitosterol, Sitosterol-d-glucoside

Flavonoids:
Morusin, Cyclomorusin, Kuwanon A, Kuwanon B, Kuwanon C, Kuwanon D, Kuwanon E, Kuwanon F, Kuwanon G (Moracenin B, Albanin F), Kuwanon H (Moracenin A, Albanin G), Moracenins, Oxydihydromorusin (=morusinol), Kuwanon L, Morusin, Sanggenon D, Sanggenon C

Coumarins:
Umbelliferone, Scopoletin

Amino acids:
Betaine

Other nitrogen compounds:
Adenine
Pharmacological effects Analgesia, cathartic, antiinflammatory (water soluble fraction), mild anti-tumor (hot water extractable fraction). Decrease in blood sugar (decoction, ethanol extract).
Indications As an antitussive, expectorant, antiphlogistic diuretic, it is applied to treat bronchitis, cough, oliguria and edema.
Diseases Bronchitis, Cough, Dyspnea, Rapid breathing, Edema, Oliguria
Formulas ogibekkoto , kagaisan , kyososan , gokoto , seihaito , zenshikunshito , zosonmokuboito , bunshinkiin , henseishinkiin , hohaito , hontonto (kinkiyoryaku) , maorenshoshakushozuto
Meridian tropism Lung
Property Cold
Flavor Sweet, Acrid/pungent
Classification in "Shen-non Ben-cao Jing" Middle
TCM: Classification Expectrants and antitussives
TCM: Medicinal effects To remove heat from the lung, to relieve asthma, and to induce diuresis.: For cough and asthma caused by heat in the lung, anasarca with oliguria, and edema of face.
Remarks Listed in the Japanese Pharmacopoeia 18th ed.
References TN: T. Namba & Y. Tsuda ed., Outline of Pharmacognosy, a Textbook, 3rd ed., Nankodo Co., Ltd., Tokyo, 1998.
DNA sequences of medicinal plants
Gene Region
Nuclear Chloroplast Mitochondria
Botanical source: Plant name 5Ss 18S ITS1 5.8S ITS2 26S others trnH-psbA matK trnK trnK-rps16 trnT-L trnL trnL-F rbcL rpoC1 ndhF others
Morus alba Linné (IPNI:30051955-2)
rbcL-accD
 AB194397
rps16
  EF687667
 EF687668
 EF687670
 EF687671
 EF687679
 EF687682
Morus mongolica C.K.Schneider (IPNI:584372-1)
rps16
 EF687675
 

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Section of Pharmacognosy,
Division of Medicinal Resources,
Department of Research and Development,
Institute of Natural Medicine,
University of Toyama
2630 Sugitani, Toyama 930-0194 Japan
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