Menu  → Scientific information on crude drugs  → 
Sinomenium Stem and Rhizome
Sinomenium Stem and Rhizome
Market name:防已
Photo location:Museum of Materia Medica, Inst. of Nat. Med.
TMPW No.:2982A1
Sinomenium acutum
Plant name:Sinomenium acutum
Photo location:Gifu Pref.
Photo date:1995
Photographer:K. Komatsu

Latin name Sinomeni Caulis et Rhizoma
Botanical source: Family name Menispermaceae
Botanical source: Plant name Sinomenium acutum Rehder et E.H.Wilson (IPNI:581373-1)
Part used Viny stem and rhizome
Empirical criteria for quality selection The cross section is brown and has a pattern of chrysanthemum. The real Sinomenium stem and rhizome resembles Akebia stem. (TN)
Constituents Sterols:
[S. acutum]: β-Sitosterol, Stigmasterol

Isoquinoline alkaloids:
[S. acutum]: Sinomenine, Disinomenine, Isosinomenine, Sinactine, Tuduranine, Acutumine, Acutumidine, Sinoacutine, Magnoflorine
[C. trilobus]: Trilobine, Isotrilobine, Homotrilobine, Trilobamine, Normenisarine, Cocculolidine, Magnoflorine
Pharmacological effects Antiinflammatory, antiallergic (hot water extract) antiinflammatory, analgesic, and decreases blood pressure (sinomenine).
Indications As an diuretic and painkiller, it is applied to treat nerve pain, rheumatism, arthritis and edema.
Diseases Rheumatism, Arthritis, Arthralgia, Numbness, Thirst, Edema, Pulmonary edema, Ascites, Oliguria, Itching
Formulas karogaihakuto , shozokumeito , sokeikakketsuto , dokkatsuto , boiogito , boibukuryoto , mokuboito
Meridian tropism Urinary bladder, Lung
Property Cold
Flavor Bitter, Acrid/pungent
Classification in "Shen-non Ben-cao Jing" Middle
TCM: Classification Diuretics with removing dampness
TCM: Medicinal effects To remove wind and damp, promote the circulation of channels, induce diuresis.
Used for wind and damp with numbing, swelling of joints, itching and palsy.
Remarks Listed in the Japanese Pharmacopoeia 18th ed.
References TN: T. Namba & Y. Tsuda ed., Outline of Pharmacognosy, a Textbook, 3rd ed., Nankodo Co., Ltd., Tokyo, 1998.
DNA sequences of medicinal plants
Gene Region
Nuclear Chloroplast Mitochondria
Botanical source: Plant name 5Ss 18S ITS1 5.8S ITS2 26S others trnH-psbA matK trnK trnK-rps16 trnT-L trnL trnL-F rbcL rpoC1 ndhF others
Sinomenium acutum Rehder et E.H.Wilson (IPNI:581373-1)


Information on genetic analysis

Metabolism information on chemical compounds included in crude drugs

Traditional Medical & Pharmaceutical Database

Section of Pharmacognosy,
Division of Medicinal Resources,
Department of Research and Development,
Institute of Natural Medicine,
University of Toyama
2630 Sugitani, Toyama 930-0194 Japan
TEL: +81-76-434-7601
FAX: +81-76-434-5064