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| Compound | Isorhynchophylline |
| Animal species | rat |
| Metabolism parameters |
Intravenous administration Oral administration |
| Metabolites |
Isorhynchophylline
11-Hydroxyisorhynchophylline 10-Hydroxyrhyisonchophylline 11-Hydroxyisorhynchophylline-11-O-glucuronide 10-Hydroxyisorhynchophylline-10-O-glucuronide |
| Crude drug | Uncaria Hook |
| References | 1) Wang W., Ma C. M., and Hattori M.: Metabolism and pharmacokinetics of isorhynchophylline in rats detected by LC-MS. J. Pharmaceut. Sci., 13, 27-37 (2010). 2) Wang W., Ma C. M., and Hattori M.: Simultaneous determination of rhynchophylline, isorhynchophylline, and their eight metabolites in rats. J. Trad. Med., 27, 15-29 (2010). |
| Remarks |
