Arctigenin
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| Compound | Arctigenin |
| Animal species | human intestinal microflora |
| Metabolism parameters | |
| Metabolites |
(-)-Arctigenin
(3R,4R)-3-(3,4-dihydroxybenzyl)-4-(3,4-dimethoxybenzyl)dihydrofuran-2(3H)-one (3R,4R)-4-(3,4-dimethoxybenzyl)-3-(3-hydroxybenzyl)dihydrofuran-2(3H)-one (3R,4R)-4-(3-hydroxy-4-methoxybenzyl)-3-(3-hydroxybenzyl)dihydrofuran-2(3H)-one (3R,4R)-4-(3,4-dihydroxybenzyl)-3-(3-hydroxybenzyl)dihydrofuran-2(3H)-one (-)-Enterolactone |
| Crude drug | Forsythia Fruit |
| References | 1) Xie L., Ahn E., Akao T., Abdel-Hafez A. A., Nakamura N. and Hattori M.: Transformation of arctiin to esterogenic and antiestrogenic substances by human intestinal bacteria. Chem. Pharm. Bull., 51, 378-384 (2003). 2) Gao J. J. and Hattori M.: Metabolic activation of lignans to estrogenic and anti-eatrogenic substances by human intestinal bacteria. J. Trad. Med., 22, 213-221 (2005). |
| Remarks |
