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Japanese Angelica Root
Japanese Angelica Root
当帰
Market name:当帰
Photo location:Museum of Materia Medica, Inst. of Nat. Med.
TMPW No.:4904
Angelica acutiloba
Plant name:Angelica acutiloba
Photo location:Nara Pref., Japan
Photo date:1994
Photographer:K. Komatsu

Synonym  
Latin name Angelicae Acutilobae Radix
Botanical source: Family name Umbellifera
Botanical source: Plant name - Angelica acutiloba Kitagawa (IPNI:837548-1)
- Angelica acutiloba var. sugiyamae Hikino (IPNI:60470529-2)
Part used Root
Empirical criteria for quality selection Good one is well enlarged, has no insect damage and fragrant aroma. The one of horse-tail is considered as good in quality, and the head of Angelicae Radix produced in China is superior (TN).
Constituents Other aliphatic and related compounds:
[A. acutiloba]: Falcarindiol, Falcarinol, Falcarinolone

Monoterpenoids:
[A. acutiloba]: p-Cymene, Carvacrol

Sterols:
[A. acutiloba]: β-Sitosterol

Phenylpropanoids:
[A. acutiloba]: Safrole, Isosafrole, Ferulic acid, Caffeic acid

Coumarins:
[A. acutiloba]: Bergapten, Isopimpinellin, Xanthotoxin, Scopoletin, Umbelliferone

Phthalides:
[A. acutiloba]: Ligustilide, n-Butylidenephthalide, n-Butylphthalide, Sedanonic acid lactone, Senkyunolide E, Senkyunolide F, Senkyunolide H, Senkyunolide I, Angeloylsenkyunolide F, Tokinolide A, Tokinolide B, Levistolide A

Other aromatic derivatives:
[A. acutiloba]: O-Valerophenone carboxylic acid, Vanilic acid, Biotin

Pyridine alkaloids:
[A. acutiloba]: Nicotinic acid

Pteridine derivatives:
[A. acutiloba]: Folic acid

Porphyrin derivatives:
[A. acutiloba]: Vitamin-B12
Pharmacological effects Analgesic (polyacetylenes). Antiinflammatory. Antipyretic (essential oil). Hypotensive. Increase in ocular tension. Antiallergic.
Indications For removing blood stasis of warm property, as a tonic, tranquilizer and painkiller, it is applied to treat anemia, abdominal pain, general aching of the body, irregular menstruation, dysmenorrhea, menstrual pain, blood circulation disorders and menopausal disorder.
Diseases Lightheadedness, Vertigo, Bleary eyes, Palpitation, Irregular menstruation, Menorrhalgia, Abdominal pain, Chill, Swelling and pain due to contusion, Numbness, Pyogenic dermatosis, Constipation
Formulas ishoho , ifuto , ureitsukisan , unkeito , unseiin , otsujito , otsujitokyodaio , kagenryokakusan (kyoteiken) , kamikihito , kamishimotsuto , kamishoyosan , kamishoyosankasenkyujio , karokijitsuto , kigikenchuto , kihito , kyukikyogaito , kyukichoketsuin , kyukichoketsuindaiichikagen , keigairengyoto , goshitsusan , goshakusan , gorinsan , saikoseikanto , shiunko , shikonboreito , shichimotsukokato , shimotsuto , shofusan , shoyosan , shinsentaitsuko , jiinkokato , jiinshihoto , jiketsujunchoto , jijintsujito , jijinmeimokuto , jashoshito , juzentaihoto , jurokumiryukiin , junchoto , jingyobekkoto , jingyobofuto , seishoekkito , seijokentsuto , seinetsuhokito , seinetsuhoketsuto , seihaito , sesshoin , senkanmeimokuto , senkinkeimeisan , senkin'naitakusan , zenshikunshito , sokeikakketsuto , soshikokito , zokumeito , takurishodokuin , daibofuto , choreitogoshimotsuto , tsudosan , tokiinshi , tokikenchuto , tokisan , tokishigyakukagoshuyushokyoto , tokishigyakuto , tokishakuyakusan , tokishakuyakusankaogichoto , tokishakuyakusankaninjin , tokishakuyakusankabushi , tokito , tokibaimokujinganryo , dokkatsuto , nyoshinsan , ninjin'yoeito , hachimitaikaho , fuhishomyakusan , hochuekkito , hoyokangoto , hontonto (kinkiyoryaku) , bofutsushosan , yokuininto , yokukankashakuyaku , yokukansan , yokukansankashakuyakuoren , yokukansankachimpihange , ryutanshakanto , renjuin
Meridian tropism Heart, Liver, Spleen
Property Warm
Flavor Sweet, Acrid/pungent
Classification in "Shen-non Ben-cao Jing" Middle
TCM: Classification Tonics
TCM: Medicinal effects To enrich the blood, to activate blood circulation, to regulate menstruation, relieve pain, and relax bowels.
Used for anemia with dizziness and palpitation, menstrual disorders, amenorrhea, dysmenorrhea, constipation, rheumatic arthralgia, traumatic injuries, carbuncles, boils and sores.
Remarks Listed in the Japanese Pharmacopoeia 18th ed.
References TN: T. Namba & Y. Tsuda ed., Outline of Pharmacognosy, a Textbook, 3rd ed., Nankodo Co., Ltd., Tokyo, 1998.
DNA sequences of medicinal plants
Gene Region
Nuclear Chloroplast Mitochondria
Botanical source: Plant name 5Ss 18S ITS1 5.8S ITS2 26S others trnH-psbA matK trnK trnK-rps16 trnT-L trnL trnL-F rbcL rpoC1 ndhF others
Angelica acutiloba var. sugiyamae Hikino (IPNI:60470529-2)
rpl16-rpl14
 AB199892
atpF-atpA
 AB200215
Angelica acutiloba Kitagawa (IPNI:837548-1)
rpl16-rpl14
 AB199891
atpF-atpA
  AB200214
 

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