Oral administration
| Dose | 40 mg/kg |
| K | |
| T1/2 | 1.16 ± 1.0 h ^a |
| Tmax | |
| V | |
| CL | |
| Cmax | |
| AUC | 144.3 ± 93.2 ng∙h∙ml^-1 ^a |
| Range of AUC | 0-limit |
| MRT | 2.68 ± 1.5 h ^a |
| MAT | 0.35 ± 0.2 h |
| Others | |
| Comment | a p< 0.05, b p< 0.01 compared with conventional rats; Data are expressed as means±S.D. (n = 4). Ber, berberine; M1, berberrubine; M2, thalifendine: M3, demethyleneberberine; M4, jatrorrhizine. |
| Remarks |
Others:Others unclassified into each parameter
Comment:Comment on metabolism parameters
Comment:Comment on metabolism parameters
