Oral administration
| Dose | 40 mg/kg |
| K | |
| T1/2 | 7.96 ± 2.7 h |
| Tmax | |
| V | |
| CL | |
| Cmax | |
| AUC | 1523.7 ± 448.9 ng∙h∙ml^-1 |
| Range of AUC | 0-limit |
| MRT | 24.39 ± 6.3 h |
| MAT | 4.33 ± 3.2 h |
| Others | |
| Comment | a p< 0.05, b p< 0.01 compared with conventional rats; Data are expressed as means±S.D. (n = 4). Ber, berberine; M1, berberrubine; M2, thalifendine: M3, demethyleneberberine; M4, jatrorrhizine. |
| Remarks |
Others:Others unclassified into each parameter
Comment:Comment on metabolism parameters
Comment:Comment on metabolism parameters
