Intravenous administration
| Dose | 100 mg/kg (n=8) |
| K | |
| T1/2 | 50.7 ± 33.2 |
| Tmax | 16.9 ± 5.3 min |
| V | |
| CL | |
| Cmax | 83.4 26.5* ng/mL |
| AUC | 6.60 ± 3.29 μg・min/mL |
| Range of AUC | |
| MRT | |
| MAT | |
| Others | Ae0-24h 0.026 ± 0.013 % of dose GI24h 0.28 ± 0.07 % of dose F 0.5 % |
| Comment | * The values were significantly different from 2 and 5 mg/kg p<0.05) . |
| Remarks |
Others:Others unclassified into each parameter
Comment:Comment on metabolism parameters
Comment:Comment on metabolism parameters
