Oral administration
Dose | 125 mg/kg mixed solution (containing 25 mg costunolide and 100 mg dehydrocostuslacton) |
K | |
T1/2 | 5.442 h |
Tmax | 6.000 h |
V | |
CL | Cl/F 91.62 L/h/kg |
Cmax | 0.063 L/h/kg |
AUC | 1.081 mg/Lh 1.091 1.091 |
Range of AUC | 0–48 0–∞ |
MRT | |
MAT | |
Others | Vd/F 0.176 L/kg t1/2ka 4.394 R2 0.954 |
Comment | |
Remarks |
Others:Others unclassified into each parameter
Comment:Comment on metabolism parameters
Comment:Comment on metabolism parameters