Intravenous administration
| Dose | 20 mg/kg |
| K | kel 0.211 ± 0.018 (h ± 1) serum ke 0.040 ± 0.008 (h ± 1) urine |
| T1/2 | 3.400 ± 0.272 (h) serum 12.404 ± 2.439 (h) urine |
| Tmax | |
| V | Vss 4.183 ± 0.172 l/kg |
| CL | CLrenal 0.062 ± 0.014 l/h/kg CLhepatic 0.806 ± 0.029 l/h/kg CLtot 0.868 ± 0.041 l/h/kg |
| Cmax | |
| AUC | 11.643 ± 0.535 mg ± h/ml 3.422 ± 0.082 % |
| Range of AUC | inf 72-inf extrapolated |
| MRT | 5.714 ± 0.855 h |
| MAT | |
| Others | fe 6.869 ± 1.393 % Extraction ratio (ER) 0.463 ± 0.016 |
| Comment | |
| Remarks |
Others:Others unclassified into each parameter
Comment:Comment on metabolism parameters
Comment:Comment on metabolism parameters
