Verproside
|
| Compound | Verproside |
| Animal species | Sprague-Dawley rat |
| Metabolism parameters |
Intravenous administration Intravenous administration Intravenous administration Intravenous administration Intravenous administration Intravenous administration |
| Metabolites |
Verproside
|
| Crude drug | |
| References | 1) Eun Jeong Park, Hyun Sook Lee, Sei-Ryang Oh, Hyeong-Kyu Lee, and Hye Suk Lee: Pharmacokinetics of verproside after intravenous and oral administration in rats. Arch. Pharm. Res. 32: 559-564 (2009). 2) Eun Jeong Park, Sei-Ryang Oh, Hyeong-Kyu Lee and Hye Suk Leea: Liquid chromatography–mass spectrometry for the simultaneous determination of the catalpol-related iridoid glucosides, verproside, isovanilloylcatalpol, catalposide and 6-O-veratroyl catalpol in rat plasma LC/MS analysis of the catalpol-related iridoid glucosides in rat plasma. Biomed. Chromatogr., 23: 980–986 (2009). |
| Remarks | ※Pharmacokinetic parameters of verproside after intravenous administration Values represent mean ± SD. * The values were significantly different from 2 and 5 mg/kg (p<0.05). Eun Jeong Park et al., Arch. Pharm. Res. 32: 559-564 (2009). ※Pharmacokinetic parameters of verproside after oral administration Values represent mean ± SD. * The values were significantly different from 2 and 5 mg/kg (p<0.05). Eun Jeong Park et al., Arch. Pharm. Res. 32: 559-564 (2009). |
