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Compound | Methylephedrine |
Animal species | human |
Metabolism parameters | |
Metabolites |
Methylephedrine
|
Crude drug | Ephedra Herb |
References | 1) Yan-Ming Liu, Wei Tian, Yu-Xiu Jia and Hai-Yan Yue, Simultaneous determination of methylephedrine and pseudoephedrine in human urine by CE with electrochemiluminescence detection and its application to pharmacokeinetics. Simultaneous determination of methylephedrine and pseudoephedrine. Biomed. Chromatogr., 23: 1138–1144 (2009). |
Remarks | A novel method for the determination of ephedra alkaloids (methylephedrine and pseudoephedrine) was developed by electrophoresis capillary (CE) separation and electrochemiluminesence detection (ECL). The two ephedra alkaloids with very similar structures were well separated and detected under the optimum conditions. The proposed method was successfully applied to the determination of methylephedrine and pseudoephedrine in human urine and the monitoring of pharmacokinetics for PSE. [Liu et al., Biomed. Chromatogr., 23: 1138–1144 (2009)] |