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Compound | Caffeic acid |
Animal species | human intestinal bacteria Eubacterium sp. strain SDG-2 |
Metabolism parameters | |
Metabolites |
Caffeic acid
3-(3, 4-Dihydroxyphenyl)-propionic acid 3-(3-Hydroxyphenyl)-propionic acid |
Crude drug | Japanese Angelica Root , Perilla Herb |
References | 1) Wang L., Meselhy M. R., Li Y., Nakamura N., Min B., Qin G. and Hattori M.: The heterocyclic ring fission and dehydroxylation of catechins and related compounds by Eubacterium sp. strain SDG-2, a human intestinal bacterium. Chem. Pharm. Bull., 49, 1640-1643 (2001). |
Remarks | ・Incubation of caffeic acid with Eubacterium sp. strain SDG-2 Caffeic acid (50 mg in 1 ml MeOH) was anaerobically incubated with a bacterial suspension (100 ml) for 2 d. The reaction mixture was then treated as usual to give 3-(3,4-dihydroxyphenyl)propionic acid (8 mg) and 3-(3-hydroxyphenyl)propionic acid (10 mg). [Wang et al., Chem. Pharm. Bull., 49, 1640-1643 (2001)] |