6-Shogaol
|
| Compound | 6-Shogaol |
| Animal species | human |
| Metabolism parameters |
Oral administration Oral administration Oral administration |
| Metabolites |
6-Shogaol
|
| Crude drug | Ginger , Processed Ginger |
| References | 1) Yanke Yu, Suzanna Zick, Xiaoqin Li, Peng Zou, Benjamin Wright, and Duxin Sun, Examination of the pharmacokinetics of active ingredients of ginger in humans. The American Association of Pharmaceutical Scientists Journal 2011, DOI: 10.1208/s12248-011-9286-5. 2) Marie‐Lou Gauthier, Jennifer Douat, Pascal Vachon and Francis Beaudry Characterization of [6]‐gingerol metabolism in rat by liquid chromatography electrospray tandem mass spectrometry. Biomed Chromatogr. 2011, DOI: 10.1002/bmc.1585. 3) Suzanna M. Zick, Zora Djuric, Mack T. Ruffin, Amie J. Litzinger, Daniel P. Normolle, Meihua Rose Feng, and Dean E. Brenner, Pharmacokinetics of 6-, 8-, 10-gingerols and 6-shogaol and conjugate metabolites in healthy human subjects. Cancer Epidemiol Biomarkers Prev. 17: 1930–1936 (2008). DOI: 10.1158/1055-9965.EPI-07-2934. |
| Remarks | 被験者にPure Encapsulation's ginger を投与した後、経時的に血清中のgingerolおよびshogaol化合物濃度をHPLCで分析した。[Zick et al., Cancer Epidemiol Biomarkers Prev. 17: 1930–1936 (2008)] Pharmacokinetic parameters of 6-shogaol and other related compounds Mean±SD Pharmacokinetic parameters of 6-gingerol and other related compounds Mean±SD Pharmacokinetic parameters of 8-gingerol and other related compounds Mean±SD Pharmacokinetic parameters of 10-gingerol and other related compounds Mean±SD [Zick et al., Cancer Epidemiol Biomarkers Prev. 17: 1930–1936 (2008)] |
