Arctin

Compound Arctin 
Animal species human intestinal bacteria 
Metabolism parameters  
Metabolites Arctiin
(-)-Arctigenin
(2R,3R)-2-(3',4'-Dihydroxybenzyl)-3-(3",4"-dimethoxybenzyl) butyrolactone
(2R,3R)-2-(3'-Hydroxybenzyl)-3-(3",4"-dimethoxybenzyl) butyrolactone
(2R,3R)-2-(3'-hydroxybenzyl)-3-(3"-hydroxy-4"-methoxybenzyl) butyrolactone
(2R,3R)-2-(3'-Hydroxybenzyl)-3-(3",4"-dihydroxybenzyl) butyrolactone
(-)-Enterolactone
Crude drug Burdock Fruit , Forsythia Fruit 
References 1) Xie L., Ahn E., Akao T., Abdel-Hafez A. A., Nakamura N. and Hattori M.: Transformation of arctiin to esterogenic and antiestrogenic substances by human intestinal bacteria. Chem. Pharm. Bull., 51, 378-384 (2003).
2) Gao J. J. and Hattori M.: Metabolic activation of lignans to estrogenic and anti-eatrogenic substances by human intestinal bacteria. J. Trad. Med., 22, 213-221 (2005). 
Remarks  
 

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Information on genetic analysis

Information of bioassay

Metabolism information on chemical compounds included in crude drugs

Traditional Medical & Pharmaceutical Database


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