Berberine
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| Compound | Berberine |
| Animal species | male Wistar rats |
| Metabolism parameters |
Oral administration Oral administration Oral administration Oral administration Oral administration Oral administration Oral administration Oral administration Oral administration Oral administration |
| Metabolites |
Berberine
Berberrubine Thalifendine Demethyleneberberine Jatrorrhizine |
| Crude drug | Coptis Rhizome , Corydalis Tuber , Nandina Fruit , Phellodendron Bark |
| References | 1) Zuo F., Nakamura N. and Hattori M.: Pharmacokinetics of berberine and its main metabolites in conventional and pseudo germ-free rats determined by liquid chromatography/ion trap mass spectrometry. Drug Metab. Dispos., 34, 2064-2072 (2006). |
| Remarks |
